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Chemical
Pleurodesis for Malignant Pleural
Effusions or Fluids in Lungs
(August 26th, 2009)
Pleural
effusion is the abnormal accumulation
of fluid-like substances around the
pleura which is the area between the
parietal and visceral pleura that
covers the lungs and surrounds the
chest walls. When this fluid accumulates
or starts to form in the pleura, the
patient can suffer from dyspnea (shortness
of breath), have difficulty in breathing
and have a faster heart beat rate,
which makes life very unpleasant.
Note that these symptoms do not occur
suddenly, they tend to develop over
a gradual period of time and pleural
effusions or the fluids in the pleura
can be detected via a chest x-ray
or more advanced screening methods
such as Computed Tomography (CT) scans.
The image on the left shows the lung
linings in the pleura and the pleural
space without any build up of fluids,
with a normal length between the parietal
& visceral pleura, as well as
normal functioning lungs.
The
treatment designed to stop the accumulation
of fluids in the pleura and help relieve
the unpleasant symptoms of the disease
is known as pleurodesis. Pleurodesis
seals the open spaces between the
parietal & visceral pleura with
a chemical such that the two areas
become attached to each other and
stick together. The type of chemical
used includes sterile talc or chemotherapy
powder. The concept behind pleurodesis
treatment is that since there are
no spaces between the parietal &
visceral pleura, fluids cannot form
or accumulate between these spaces
due to lack of space. And usually
pleurodesis is a quick procedure that
can be done at your local hospital;
however if you have more fluids accumulated
than normal, you will have to stay
overnight in the hospital for full
drainage of fluids. The image on the
right shows the lung linings in the
pleura with the pleural space accumulated
with fluids between the pleural spaces
(parietal & visceral pleura) as
well as an arrow showing pleural effusions.
How
is Pleurodesis Performed?
One
of the ways pleurodesis is performed
is via use of a chest tube that is
placed in the lower part of the chest,
near the underarm. The job of the
chest tube is to collect & drain
out fluids from the pleural spaces
in to a collection contained called
Pleur-e-vac. This container is usually
connected to a suction to allow adequate
& smooth drainage of the fluid
without having to remove the chest
tube from the area near the underarm
twice. Once all the fluids have been
extracted from the pleural spaces
and accumulated in the collection
container, a solution of talc is applied
to seal the empty spots between the
parietal & visceral pleura.
Pleurodesis
is usually performed using a procedure
called Video-assisted thoracoscopic
(VATS) surgery during which a thoracoscope
is inserted in to your chest through
a small incision made while you are
under a general anesthetic. A thorascope
is a tiny fiber-optic camera that
lets the surgeon see the surgery equipment
that is inserted through your chest
to rain out the pleural fluids that
have accumulated. Once the drainage
process is complete, a talc solution
or relevant chemical agent is inserted
in to the chest tube to clamp together
the parietal and the visceral pleura
such that there is no empty space
between the two. Your surgeon might
ask you to change positions and flip
backwards in order to allow the talc
solution to settle in well and distribute
thoroughly in the chest. This image
shows how the chest tube is inserted
in to the pleural space and how ascites
or pleural fluids are extracted from
the pleural cavities.
Symptoms
Expected to Occur after Chemical Pleurodesis
Carrying
out a chemical pleurodesis function
comes with its own set of side effects
including:
- Fever
occuring 2-4 hours after drainage
of fluids
- Feeling
of pain around your underarm area
where the chest tube was inserted
or when taking a deep breath
- You
must not take any anti- inflammatory
agents or Ibuprofen for at least 48
hours after the pleurodesis operation.
- You
will feel irritation which is important
to close the empty space between the
visceral & parietal pleura, so
do not try to scratch away the irritation,
let it do its course of work.
- You
might easily become constipated if
you are taking pain medicine.
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